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Individual identification of monozygotic twins by CNV analysis

Research Project

Project/Area Number 24790645
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Legal medicine
Research InstitutionNihon University

Principal Investigator

IZAWA Hikaru  日本大学, 歯学部, 助教 (30514103)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords一卵性双生児 / 個人識別 / CNV解析 / aCGH法 / aCGH
Research Abstract

Is performed CNV analysis by aCGH method using a microarray as a sample of blood for six monozygotic twins , an attempt was made to CNV analysis by real-time PCR using SYBR Green as a sample oral mucosal epithelium for nine monozygotic twins.
The CNV analysis by aCGH method of six monozygotic twins, CNV is found in common to 2061bp on chromosome 2 of the two sets. There was no CNV that are found in common to all, personal identification was possible CNV is present in 12 people six monozygotic twins.
Also was subjected to real-time PCR method to prepare a primer about the second chromosome, personal identification was possible with the exception of the (six months old) a pair.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (6 results)

All 2013 2012 Other

All Presentation (6 results)

  • [Presentation] aCGH法を応用したCNV解析による一卵性双生児の個人識別2013

    • Author(s)
      伊澤光、堤博文、丸山澄、小室歳信
    • Organizer
      第97次日本法医学会学術全国集会
    • Place of Presentation
      札幌
    • Year and Date
      2013-06-27
    • Related Report
      2013 Final Research Report
  • [Presentation] 一卵性双生児の個人識別を可能にしたCNV解析2013

    • Author(s)
      伊澤光、丸山澄、堤博文、小室歳信
    • Organizer
      第64回日本大学歯学会総会・学術大会
    • Place of Presentation
      東京
    • Year and Date
      2013-05-20
    • Related Report
      2013 Final Research Report
  • [Presentation] aCGH法を応用したCNV解析による一卵性双生児の個人識別2013

    • Author(s)
      伊澤 光、堤 博文、丸山 澄、小室歳信
    • Organizer
      第97次日本法医学会学術全国集会
    • Place of Presentation
      札幌 ロイトン札幌
    • Related Report
      2013 Annual Research Report
  • [Presentation] CNV解析による一卵性双生児の個人識別-リアルタイムPCR法による-2012

    • Author(s)
      伊澤光、堤博文、丸山澄、網干博文、小室歳信
    • Organizer
      第81回日本法医学会学術関東地方集会
    • Place of Presentation
      群馬
    • Year and Date
      2012-10-20
    • Related Report
      2013 Final Research Report
  • [Presentation] 一卵性双生児の個人識別を可能にしたCNV解析

    • Author(s)
      伊澤 光
    • Organizer
      第64回日本大学歯学会総会・学術大会
    • Place of Presentation
      日本大学歯学部(東京)
    • Related Report
      2012 Research-status Report
  • [Presentation] CNV解析による一卵性双生児の個人識別(第5報)

    • Author(s)
      伊澤 光
    • Organizer
      第81回日本法医学会学術関東地方集会
    • Place of Presentation
      高崎シティーギャラリー(群馬)
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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