| Project/Area Number |
24790654
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | Tohoku University |
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Principal Investigator |
Tomita Naoki 東北大学, 大学病院, 助教 (00552796)
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| Co-Investigator(Renkei-kenkyūsha) |
TSUBOTA Megumi 岩手医科大学, 医学部, 講師 (20419998)
SATOH Michihiro 東北大学, 大学病院, 特別研究員(PD) (70717892)
OHKUBO Takayoshi 帝京大学, 医学部, 教授 (60344652)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 大脳白質病変 / 無症候性脳梗塞 / 脳萎縮 / 無症候性脳出血 / 脳微小出血 / 手段的ADL / 老年症候群 / 脳委縮 / 微小脳出血 / ラクナ梗塞 / 無症候性脳血管障害 / データベース |
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| Outline of Final Research Achievements |
At the community-based cohort, both lacunar infarcts and white matter hyperintensity were significantly associated with the decline of higher-level daily functions after 7-year follow-up. Lacunar infarcts were strongly associated with the decline, rather than white matter hyperintensity. Lacunar infarcts were related to decline in intellectual activity.
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