MicroRNA of the non-alcoholic steato-hepatitis
| Project/Area Number |
24790706
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Gastroenterology
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| Research Institution | Kagawa University |
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Principal Investigator |
TANI Joji 香川大学, 医学部附属病院, 助教 (00596075)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 非アルコール性脂肪肝炎 / miRNA / NASH / NAFLD / メトホルミン / マイクロRNA |
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| Outline of Final Research Achievements |
NASH increases year by year, and NASH becomes the non-viral liver cancer cause.
We analyzed those causes using microRNA and tried application to a diagnosis, treatment by identifying the cause micro RNA. Using the mouse of two kinds of non-alcoholic steato-hepatitis models, we extracted microRNA from the liver of the mouse and identified microRNA about extension. Also, we identified the microRNA which changed by giving metformin and galectin 9. We tried application in future by identifying microRNA with the serum of patients with non-alcoholic hepatitis.
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Report
(4 results)
Research Products
(4 results)
