Analysis of physiological functions and translationl reserchs of Intrinsic Cardiac Adrenergic Cell in transplanted hearts
Project/Area Number |
24790780
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Circulatory organs internal medicine
|
Research Institution | Keio University |
Principal Investigator |
TAMURA YUICHI 慶應義塾大学, 医学部, 特任助教 (00468498)
|
Project Period (FY) |
2012-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 分子心臓病態学 / 心臓移植 / 交感神経 |
Research Abstract |
We identified the Intrinsic Cardiac Adrenergic Cell (ICA cell) are derived from neural crest by analyzing P0-Cre x Floxed-GFP transgenic mice. We found a promoting factor for the proliferation and differentiation into ICA cell as NGF. And we confirmed the contraction and heart rate of transplanted hearts were affected with the development of ICA cell.
|
Report
(3 results)
Research Products
(4 results)