| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
fNIRS is a noninvasive and unrestrictive method of functional neuroimaging. Making the most of fNIRS’s merits, we have explored the neural substrate of inhibitory and attentional controls in ADHD children. Firstly, our fNIRS-based measurements successfully visualized the hypoactivation pattern in the right prefrontal and parietal cortex during an inhibition and attention task in ADHD children compared with typically developing control at a group level using fNIRS. Secondly, we clarified a method of individual classification between ADHD and typically developing control children using fNIRS with high classification accuracy with 90% sensitivity. Finally, we explored neuropharmacological effect of ADHD medications using double-blinded placebo study. Then the reduction of right prefrontaland parietal activation was normalized after taking ADHD medications, such as MPH and ATX.
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