| Project/Area Number |
24791123
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | Japan Women's University |
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Principal Investigator |
Ota Mariko 日本女子大学, 人間社会学部, 助教 (50599412)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 脳・神経 / 新生児発達 / 呼吸 / 自律神経 / 脳波 / 皮質血行動態 |
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| Outline of Final Research Achievements |
The aim of this research is to evaluate the development of neonatal cortical activities contributing to the regulation of respiratory activities. We especially focused on reciprocal cortico-respiratory interactions while hearing the mother's voice, and simultaneously recorded respiratory chest movements, heart rate, electroencephalographic activity, and cerebral hemoglobin concentration changes in near-term and full-term neonates. The results suggest that hearing the mother's voice promotes the slow increase in respiratory rate associated with high-level attention and it also softens the rapid increase in respiratory rate. These effects of the mother's voice on respiratory activity seem to be mediated by the high-order function in the neonatal prefrontal cortex, and the neural function for respiratory regulation may be sufficiently developed by 38-week old.
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