Effects of lipid nutrition and lipid metabolism on chronic lung disease in very low birth weight infants
| Project/Area Number |
24791124
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | Juntendo University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 早産児 / 慢性肺疾患 / 脂質 / DHA / 脂肪酸 / 極低出生体重児 / 栄養 / リポ蛋白 |
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| Research Abstract |
We investigated the relation with chronic lung disease and lipid profiles in preterm infants. The relations with respiratory disorder and lipids profile at birth in preterm infants revealed that serum triglyceride levels and apoA-I levels significantly decreased in preterm infants with respiratory disorder. The fatty acid composition of the erythrocyte membrane was analysed at 14 and 28 days of age. The Arachidonic acid levels significantly increased, whereas alpha-linolenic acid significantly decreased, in very low birth weight infants with chronic lung disease at both time points. The results showed that lipids may influence the development of chronic lung disease and lung maturity in preterm infants.
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Report
(3 results)
Research Products
(8 results)
