Developmental neuro-scientific study on the functional connectivity hypothesis of ASD
| Project/Area Number |
24791218
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Psychiatric science
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| Research Institution | Nagasaki University |
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Principal Investigator |
DOI Hirokazu 長崎大学, 医歯(薬)学総合研究科, 講師 (40437827)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | ASD / 機能的連関 / 遺伝子多型 / 脳波 / 発達障害 / 自閉症スペクトラム障害 / 乳児 |
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| Research Abstract |
It is well-established that early intervention to children with autism-spectrum disorders greatly improves their later adaptation to the social world.Recent studies show that some of core symptoms of autism-spectrum disorders is attributable to the impairment of the functional connectivity in the neural system. On the basis of this, it might be possible to develop an early screening measure by quantifying the functional connectivity from infants EEG. To this end, an exploratory investigation was conducted on what kind of EEG measurement paradigm is suitable for the measurement of infants functional connectivity. The preset study also investigated a biological marker linked to infants social communication ability that can improve the screening accuracy when used conjointly with the functional connectivity measure. The results have shown a trend-level significance in the relation between visual attention towards social stimuli and the genotype of neurotransmitter-related gene.
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Report
(3 results)
Research Products
(8 results)
