Effects of N-acetylcysteine in subjects with an at-risk mental state
Project/Area Number |
24791239
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Psychiatric science
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Research Institution | St. Marianna University School of Medicine |
Principal Investigator |
Nobumi Miyake 聖マリアンナ医科大学, 医学部, 講師 (60534237)
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Project Period (FY) |
2012-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
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Keywords | N-acetylcysteine / At-Risk Mental State / Nアセチルシステイン / Nアセチルシステイン |
Outline of Final Research Achievements |
The aim of this study was to evaluate the effects of N-acetylcysteine (a glutathione precursor) on prevention of psychosis, cognitive function and functional capacity in subjects with an at-risk mental state (ARMS). The results suggest that N-acetylcysteine may be safe and may also have beneficial delayed effects on cognitive functions and functional capacity. To the best of our knowledge, this is the first report which examined the effects of N-acetylcysteine on clinical symptoms and functioning in subjects with an ARMS, although it is preliminary.
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Report
(5 results)
Research Products
(7 results)
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[Presentation] Effects of N-acetylcysteine on clinical symptoms and functioning in subjects with at-risk mental state: a case series.2014
Author(s)
Nobumi Miyake, Seiya Miyamoto, Yusuke Yamashita, Yuriko Ninomiya, Tomomi Tenjin, Shin Ogino, Hisashi Harada, Jun Arai, Sachiko Tsukahara, Yukie Ito, Masanori Tadokoro, Taku Iwakura, Noboru Yamaguchi
Organizer
IEPA 2014
Place of Presentation
東京 新宿区 京王プラザホテル
Year and Date
2014-11-19
Related Report
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[Presentation] Effects of N-acetylcysteine on clinical symptoms in subjects with at-risk mental state: a case series.2014
Author(s)
Nobumi Miyake, Seiya Miyamoto, Yusuke Yamashita, Yuriko Ninomiya, Tomomi Tenjin, Shin Ogino, Hisashi Harada, Jun Arai, Haruki Teramoto, Sachiko Tsukahara, Yukie Ito, Masanori Tadokoro, Taku Iwakura, Hisao Nakamura, Noboru Yamaguchi
Organizer
29th CINP World Congress 2014
Place of Presentation
Vancouver, Canada
Year and Date
2014-06-22 – 2014-06-26
Related Report
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