Project/Area Number |
24791261
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Radiation science
|
Research Institution | Hokkaido University |
Principal Investigator |
TAKAO Seishin 北海道大学, 医学(系)研究科(研究院), 助教 (10614216)
|
Project Period (FY) |
2012-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 放射線治療 / コーンビームCT / 四次元再構成 / CBCT |
Research Abstract |
We have proposed a novel method for four-dimensional (4D) cone-beam computed tomography (CBCT) reconstruction with real-time tumor tracking technique. In the real-time tumor tracking, a fiducial marker inserted near the tumor is detected in the orthogonal fluoroscopic images. The three-dimensional position of the marker is calculated every 33 msec with an accuracy of 1 mm. According to the position of the marker, projection images can be classified into some phases. Four dimensional CBCT reconstruction is therefore available in each phase. Feasibility of the 4D CBCT reconstruction was evaluated through the experience using the testing machine, which has the same imaging devices in the proton therapy system in Hokkaido University Hospital. Additionally, characteristics of intrafractional baseline shift of tumor motion were analyzed to investigate efficacy of the 4D CBCT reconstruction method. Through the study, the feasibility and efficacy of the 4D CBCT reconstruction was confirmed.
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