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Establishment of the appropriate dose constraints of the critical organs in the combination of brachytherapy and intensity-modulated radiation therapy for prostate cancer

Research Project

Project/Area Number 24791284
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionKanazawa University

Principal Investigator

Kumano Tomoyasu  金沢大学, 大学病院, 講師 (20377386)

Research Collaborator TAKANAKA Tsuyoshi  
TAKAMATSU Shigeyuki  
MIZUNO Ei-ichi  
SHIBATA Satoshi  
FUJITA Shinji  
MIZUHATA Miyu  
NAMIKI Mikio  
MIZOKAMI Atsushi  
KONAKA Hiroyuki  
KITAGAWA Yasuhide  
KURATA Yu-ichi  
UEDA Shin-ichi  
Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2014: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2013: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywords放射線治療 / 小線源治療 / 強度変調放射線治療 / 前立腺癌
Outline of Final Research Achievements

The purpose of the study was to clarify the appropriate dose constraints of the critical organs in the combination of brachytherapy and intensity-modulated radiation therapy for intermediate/high risk prostate cancer. We examined the dose of each critical organ in the treatment planning of both treatment and the frequency of the adverse events. We showed that this combination therapy was safe without serious adverse event if satisfying the proposed dose constraints for the critical organ (urethra, rectum, bladder and bowel) in each of brachytherapy and IMRT.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (7 results)

All 2016 2015 2014 Other

All Presentation (7 results) (of which Invited: 1 results)

  • [Presentation] 前立腺癌に対する全骨盤IMRTの治療経験2016

    • Author(s)
      水畑美優 熊野智康
    • Organizer
      日本医学放射線学会第159回中部地方会
    • Place of Presentation
      名古屋市立大学(愛知県・名古屋市)
    • Year and Date
      2016-01-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] 前立腺組織内照射をより円滑に進めるために2015

    • Author(s)
      熊野智康
    • Organizer
      第103回日本泌尿器科学会総会教育シンポジウム
    • Place of Presentation
      ANAクラウンプラザホテル金沢(石川県・金沢市)
    • Year and Date
      2015-04-19
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 当院における前立腺癌に対する高線量率組織内照射併用IMRTの経験2015

    • Author(s)
      熊野智康
    • Organizer
      日本医学放射線学会第157回中部地方会
    • Place of Presentation
      名古屋大学医学部鶴友会館
    • Year and Date
      2015-02-01
    • Related Report
      2014 Research-status Report
  • [Presentation] 前立腺癌に対する骨盤リンパ節領域への強度変調放射線治療(IMRT)の初期経験2014

    • Author(s)
      熊野智康
    • Organizer
      日本放射線腫瘍学会第27回学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-12-11
    • Related Report
      2014 Research-status Report
  • [Presentation] 中高リスク前立腺癌に対するIMRT併用高線量率組織内照射の治療経験2014

    • Author(s)
      熊野智康
    • Organizer
      日本放射線腫瘍学会小線源治療部会第16回学術大会
    • Place of Presentation
      幕張メッセ国際会議場
    • Year and Date
      2014-05-31
    • Related Report
      2014 Research-status Report
  • [Presentation] 前立腺癌に対する強度変調放射線治療(IMRT)併用高線量率組織内照射の初期経験

    • Author(s)
      熊野智康
    • Organizer
      日本放射線腫瘍学会小線源治療部会第15回学術大会
    • Place of Presentation
      九州大学医学部百年講堂
    • Related Report
      2013 Research-status Report
  • [Presentation] 高リスク前立腺癌に対する全骨盤IMRT併用高線量率組織内照射の初期経験

    • Author(s)
      熊野智康
    • Organizer
      日本放射線腫瘍学会第26回学術大会
    • Place of Presentation
      リンクステーションホール青森
    • Related Report
      2013 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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