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Development of dose evaluation and treatment planning system of intensity modulated radiation therapy considering dose uncertainties

Research Project

Project/Area Number 24791297
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionNiigata University

Principal Investigator

UTSUNOMIYA Satoru  新潟大学, 医歯(薬)学総合研究科, 助教 (50570868)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords強度変調放射線治療 / 不確かさ / 放射線治療計画 / multi-leaf collimator / 医学物理学 / 感度解析 / マルチリーフコリメータ
Outline of Final Research Achievements

Dose uncertainties in intensity modulated radiation therapy (IMRT) were analyzed qualitatively and quantitatively to create a numerical model to describe those dose uncertainties. We developed a method of creating a robust treatment plan against dose uncertainties due to patient setup error, and a method of quantifying and visualizing dose uncertainties due to error in multi-leaf collimator (MLC) modeling parameters appeared in commissioning of treatment planning system in dose distributions. Based on our developed method, a stable delivery of IMRT and maintaining its accuracy may be feasible even if there are some dose uncertainties which potentially affect to dose delivery accuracy of IMRT.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (10 results)

All 2015 2014 2013 Other

All Journal Article (4 results) (of which Peer Reviewed: 3 results) Presentation (6 results)

  • [Journal Article] 強度変調放射線治療における線量検証の標準化に向けた調査研究2015

    • Author(s)
      中村光宏、伊良皆拓、高宮大義、小野智博、秋元麻未、椋本宜学、石原佳知、宇都宮悟、椎木健裕、宮部結城、佐藤清香、門前一
    • Journal Title

      医学物理

      Volume: 34 Pages: 208-217

    • NAID

      130005114863

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Superiority of a soft tissue-based setup using cone-beam computed tomography over a bony structure-based setup in intensity-modulated radiotherapy for prostate cancer2015

    • Author(s)
      Hiraku Sato, Eisuke Abe, Satoru Utsunomiya, Motoki Kaidu, Nobuko Yamana, Kensuke Tanaka, Atsushi Ohta, Mika Obinata, Junyang Liu, Gen Kawaguchi, Katsuya Maruyama, Fumio Ayukawa, and Hidefumi Aoyama
    • Journal Title

      Journal of Applied Clinical Medical Physics

      Volume: to be determined

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] IMRT治療計画:最適化における様々な工夫2014

    • Author(s)
      宇都宮悟
    • Journal Title

      臨床放射線

      Volume: Vol.59 No.1 Pages: 227-230

    • Related Report
      2013 Research-status Report
  • [Journal Article] A feasibility study on reduction of the entrance-surface dose to neonates by use of a new digital mobile X-ray system2013

    • Author(s)
      Utsunomiya S, Monzen H, Akimoto M, Mukumoto N, Ishihara Y, Shiinoki T, Nakamura M, Miyabe Y, Sato S, Matsuo S, Hiraoka M.
    • Journal Title

      Radiol Phys Technol.

      Volume: 6 Issue: 1 Pages: 157-61

    • DOI

      10.1007/s12194-012-0182-1

    • NAID

      120005241786

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] A Sensitivity Analysis for Evaluating Dosimetric Impact of MLC Modeling Parameter Accuracy On IMRT Treatment Plans2014

    • Author(s)
      Satoru Utsunomiya
    • Organizer
      AAPM 56th Annual Meeting & Exhibition
    • Place of Presentation
      Austin, Texas, USA
    • Year and Date
      2014-07-20 – 2014-07-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] Dosimetric impact of MLC parameters on IMRT treatment plans2014

    • Author(s)
      Naoki Shibuya
    • Organizer
      第107回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-04-10 – 2014-04-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] 感度解析を用いた前立腺IMRT治療プランの頑強性評価法とその臨床応用

    • Author(s)
      宇都宮悟
    • Organizer
      第128回日本医学放射線学会 北日本地方会
    • Place of Presentation
      新潟市
    • Related Report
      2013 Research-status Report
  • [Presentation] オーバーラップ体積比率を基にした予測関数による前立腺IMRT治療計画の簡便化

    • Author(s)
      宇都宮悟
    • Organizer
      第27回日本高精度放射線外部照射研究会
    • Place of Presentation
      東京都
    • Related Report
      2013 Research-status Report
  • [Presentation] 感度解析を用いたIMRT治療プランの頑強性評価法の開発

    • Author(s)
      宇都宮悟
    • Organizer
      第103回日本医学物理学会学術大会
    • Place of Presentation
      横浜市
    • Related Report
      2012 Research-status Report
  • [Presentation] 感度解析を用いた前立腺IMRT 治療プランの頑強性評価法とその臨床応用

    • Author(s)
      宇都宮悟
    • Organizer
      日本放射線腫瘍学会第25回学術大会
    • Place of Presentation
      東京都
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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