| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Research Abstract |
Adipose tissue is known as energy storage and also heat generator at the brown adipose tissue. Excess amount of energy intake such as sugar and fat lead obesity, in which the adipose tissue hold extra lipid and also secret inflammation cytokine. Imaging devices are used for diagnosis of obesity. MRI is one of the imaging tool and able to observe not only the area of adipose tissue but also used for analysis of lipid composition in detail.
In this study, multiple quantum coherence MRI method was used for imaging lipid composition in vivo using model animal under various conditions. As the results of time course observation with induced obesity, it was revealed that the lipid composition of saturated-unsaturated lipid was change at the adipose tissue.
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