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Improvement of detectability ureteral cancer by using Dual Energy CT

Research Project

Project/Area Number 24791309
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionHiroshima University

Principal Investigator

HONDA Yukiko  広島大学, 大学病院, 病院助教 (60604486)

Research Collaborator HIGAKI Toru  広島大学, 大学院医歯薬保健学研究院, 特任助教 (80611334)
AWAI Kazuo  広島大学, 大学院医歯薬保健学研究院, 教授 (30294573)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
KeywordsDual Energy CT / split-bolus 法 / 尿路系腫瘍検出 / 尿路系腫瘍 / 被ばく低減 / 上部尿路腫瘍診断 / CTU / 上部尿路腫瘍 / 撮像法
Outline of Final Research Achievements

Standard CTU includes unenhanced-, nephrographic-, and excretory phase (UP, NP, and EP) scans. With CTU using split bolus injection of contrast media, radiation exposure is reduced because NP and EP images are acquired simultaneously. Combining DECT with split bolus injection may reduce the radiation dose further because virtual UP images can be generated by image processing. However, CTU with split bolus injection results in beam hardening artifacts due to dense iodinated urine in the ureter; this may hide subtle enhancement of the upper urinary tract and small urothelial tumors. Theoretically, on virtual monochromatic (VM) images generated from DECT data these artifacts are reduced. We developed a CTU method that combines split bolus injection and DECT technology and investigated the feasibility of our method in a phantom study.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (5 results)

All 2015 2014 2013

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (4 results)

  • [Journal Article] T-staging of urothelial carcinomas of the ureter by CT: A preliminary study of new diagnostic criteria proposed for differentiating between T2 or lower and T3 or higher2015

    • Author(s)
      Yukiko Honda
    • Journal Title

      Am J Roentgenol

      Volume: 204 Issue: 4 Pages: 792-797

    • DOI

      10.2214/ajr.14.13167

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Presentation] Novel CT urography (CTU) using split bolus injection and dual energy CT (DECT) technology: Feasibility study using a phantom2015

    • Author(s)
      本田 有紀子
    • Organizer
      第74回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2015-04-16 – 2015-04-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] CT urography (CTU) using new CT technologies: Clinical advantages of a proposed scan- and contrast injection protocol2014

    • Author(s)
      Yukiko Honda
    • Organizer
      Radiological Society of North America 2014
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2014-11-30 – 2014-12-07
    • Related Report
      2014 Annual Research Report
  • [Presentation] Differentiation between T2- and T3 urothelial cancer by using MDCT: Proposal of new diagnostic criteria2013

    • Author(s)
      Yukiko Honda
    • Organizer
      RSNA
    • Place of Presentation
      Chicago, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] CTによる尿管癌のT因子診断2013

    • Author(s)
      本田有紀子
    • Organizer
      第72回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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