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Diagnostic accuracy of the preoperative grading of glioma using quantitative analysis of 1H-MR Spectroscopy and CT perfusion

Research Project

Project/Area Number 24791343
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionFujita Health University

Principal Investigator

MURAYAMA Kazuhiro  藤田保健衛生大学, 医学部, 講師 (40622931)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
KeywordsCT灌流画像 / MRスペクトロスコピー
Research Abstract

The purpose of this study is to evaluate the diagnostic accuracy of the preoperative grading of glioma using quantitative analysis of 1H-MRS and CT perfusion image (CTP) and to investigate the optimal parameter and thresholds for grading of glioma. As a result, high level in malignant gliomas compared with the benign gliomas was shown in Lipid (guantitative value, Cr ratio), Cho (Cr ratio) of MRS, in permeability imaging of CTP.
We concluded that these parameters were useful for differentiating between benign gliomas and malignant gliomas.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (24 results)

All 2014 2013 2012 Other

All Journal Article (5 results) (of which Peer Reviewed: 1 results) Presentation (19 results) (of which Invited: 6 results)

  • [Journal Article] 中枢神経 中枢神経系における3D 画像の有用性2014

    • Author(s)
      村山和宏
    • Journal Title

      臨床画像

      Volume: 29巻 Pages: 1356-1371

    • Related Report
      2013 Final Research Report
  • [Journal Article] 中枢神経 中枢神経系における3D画像の有用性2014

    • Author(s)
      村山和宏
    • Journal Title

      臨床画像

      Volume: 29 Pages: 1356-1371

    • Related Report
      2013 Annual Research Report
  • [Journal Article] 320 列面検出器CT を用いた全脳CT Perfusion・Dynamic CTA : 頭部領域への臨床応用2012

    • Author(s)
      村山和宏
    • Journal Title

      映像情報メディカルMultislice CT

      Volume: 44巻 Pages: 96-101

    • Related Report
      2013 Final Research Report
  • [Journal Article] 320列面検出器CTを用いた全脳CT Perfusion・Dynamic CTA:頭部領域への臨床応用2012

    • Author(s)
      村山和宏
    • Journal Title

      映像情報メディカル・Multislice CT 2012 BOOK

      Volume: 44 Pages: 96-101

    • Related Report
      2012 Research-status Report
  • [Journal Article] Primary central nervous system lymphoma with lateral ventricle involvement2012

    • Author(s)
      大家祐実
    • Journal Title

      The Open Medical Imaging Journal

      Volume: 6 Pages: 103-107

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 320 列ADCT による脳血流評価2013

    • Author(s)
      村山和宏
    • Organizer
      Advanced CT MRI
    • Place of Presentation
      軽井沢
    • Related Report
      2013 Final Research Report
  • [Presentation] Evaluation of noise reduction effect of adaptive iterative dose reduction in whole-brain CT perfusion studies2013

    • Author(s)
      村山和宏
    • Organizer
      第42回日本神経放射線学会
    • Place of Presentation
      米子
    • Related Report
      2013 Final Research Report
  • [Presentation] 320 列Area Detector CT の脳神経領域への臨床応用2013

    • Author(s)
      村山和宏
    • Organizer
      第36回日本脳神経CI 学会総会
    • Place of Presentation
      広島
    • Related Report
      2013 Final Research Report
  • [Presentation] Evaluation of noise reduction effect of adaptive iterative dose reduction in whole-brain CT perfusion studies2013

    • Author(s)
      村山和宏
    • Organizer
      第72回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] Aquilion ONE Vision Edition の頭部領域への臨床応用2013

    • Author(s)
      村山和宏
    • Organizer
      第72回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] Evaluation of Noise Reduction Effect of Adaptive Iterative Dose Reduction in Whole-Brain CT Perfusion Studies2013

    • Author(s)
      村山和宏
    • Organizer
      第42回日本神経放射線学会
    • Place of Presentation
      北九州
    • Related Report
      2012 Research-status Report
  • [Presentation] 320列Area Detector CTの脳神経領域への臨床応用2013

    • Author(s)
      村山和宏
    • Organizer
      第36回日本脳神経CI学会総会
    • Place of Presentation
      広島
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Evaluation of Noise Reduction Effect of Adaptive Iterative Dose Reduction in Whole-Brain CT Perfusion Studies2013

    • Author(s)
      村山和宏
    • Organizer
      第72回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Related Report
      2012 Research-status Report
  • [Presentation] Aquilion ONE Vision Editionの頭部領域への臨床応用2013

    • Author(s)
      村山和宏
    • Organizer
      第72回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 急性期脳梗塞における閉塞血管の再開通と全脳CT Perfusionの関連性についての検討2012

    • Author(s)
      村山和宏
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Related Report
      2012 Research-status Report
  • [Presentation] 脳動脈瘤コイル塞栓術後に生じた大脳白質病変の検討2012

    • Author(s)
      村山和宏
    • Organizer
      第48回日本医学放射線学会秋季臨床大会
    • Place of Presentation
      長崎
    • Related Report
      2012 Research-status Report
  • [Presentation] 確定診断にMRIが有用であったxanthogranuloma of the sellar regionの1例2012

    • Author(s)
      小森雅子
    • Organizer
      第48回日本医学放射線学会秋季臨床大会
    • Place of Presentation
      長崎
    • Related Report
      2012 Research-status Report
  • [Presentation] 脳腫瘍における320 列Area Detector CT の役割

    • Author(s)
      村山和宏
    • Organizer
      第37回日本脳神経CI学会総会
    • Place of Presentation
      埼玉
    • Related Report
      2013 Final Research Report
  • [Presentation] 脳神経領域における320 列面検出器CT の使い方

    • Author(s)
      村山和宏
    • Organizer
      第19回熊本画像診断テクノロジー研究会
    • Place of Presentation
      熊本
    • Related Report
      2013 Final Research Report
  • [Presentation] 320 列面検出器CT を用いた脳血管・灌流画像 臨床応用を中心に

    • Author(s)
      村山和宏
    • Organizer
      第266回Open Film Conference
    • Place of Presentation
      群馬
    • Related Report
      2013 Final Research Report
  • [Presentation] 320列ADCTによる脳血流評価

    • Author(s)
      村山和宏
    • Organizer
      Advanced CT・MRI 2013
    • Place of Presentation
      軽井沢
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 脳腫瘍診断における320列Area Detector CTの役割

    • Author(s)
      村山和宏
    • Organizer
      第37回日本脳神経CI学会総会
    • Place of Presentation
      大宮
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 脳神経領域における320列面検出器CTの使い方

    • Author(s)
      村山和宏
    • Organizer
      第19回熊本画像診断テクノロジー研究会
    • Place of Presentation
      熊本
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 320列面検出器CTを用いた脳血管・灌流画像 臨床応用を中心に

    • Author(s)
      村山和宏
    • Organizer
      第266回Open Film Conference
    • Place of Presentation
      群馬
    • Related Report
      2013 Annual Research Report
    • Invited

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Published: 2013-05-31   Modified: 2019-07-29  

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