| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2015: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Outline of Final Research Achievements |
As a clinical relevance of this study, virtual monochromatic image (VMI) reconstruction at lower keV In dual-energy CT (DECT) imaging allow reduction in iodine dose, which can contribute the reduction of risk of contrast-induced nephropathy. We aimed to validate a protocol with reduced iodine load for hepatic dynamic CT using VMI. We firstly conducted a phantom experiment to determine an optimal iodine load, 30% reduction in dose, and ASiR level for VMI at 60keV (protocol A). Then we conducted a clinical study in which 54 patients suspected of liver diseases underwent three-phase dynamic CT with protocol A and the other 54 patients underwent full iodine load with single-energy CT (protocol B). The clinical study showed that no significant difference in any of the CT attenuation values between protocols A and B. In conclusion, VMIs allows 30% reduction of iodine load while maintaining comparable image quality to full iodine load with the SECT imaging.
|
