Autophagy-mediated stress response in motor neurons after transient ischemia in rabbits

Research Project

Project/Area Number	24791465
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Thoracic surgery
Research Institution	Kyushu University
Principal Investigator	FUJITA SATOSHI 九州大学, 医学(系)研究科(研究院), 共同研究員 (80621383)
Project Period (FY)	2012-04-01 – 2015-03-31
Project Status	Completed (Fiscal Year 2014)
Budget Amount *help	¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000) Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000) Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000) Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords	脊髄虚血 / オートファジー
Outline of Final Research Achievements	The purpose of the present study was to investigate the role of autophagy mediated stress response in motor neuron death after transient ischemia in rabbits. We recognized that autophagy maight be a potential factor responsible for delayed motor neuron death, and the prolonged induction of the autophagy inhibitory protein Bcl-2.

Report

(4 results)