| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
Clinical and radiological features of cerebral venous thrombosis (CVT) in Japan were analyzed based on 33 patients data retrospectively. Compared to data from western countries, hematological condition, polycythemia and anemia, as well as thrombophilia were more frequent causes of CVT in our study. The main problem in the management of CVT was diagnostic delay, which occurred in one-third of all cases. Our results suggested T2* weighted MR imaging were most helpful for early diagnosis of CVT. Almost all patients received anticoagulant therapy in acute phase, but neurological worsening mainly caused by hematoma expansion was often observed in patients with intracranial hemorrhage on admission. Neurological worsening was associated with poor outcome. Therefore, it is essential to establish more effective therapeutic strategy for CVT including early intervention of endovascular therapy. We need to confirm clinical problems identified in our ongoing CVT registry.
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