| Project/Area Number |
24791535
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Nagoya University |
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Principal Investigator |
ITO Zenya 名古屋大学, 医学部附属病院, 病院助教 (50447819)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | モニタリング / アラームポイント / 15%波形低下 / 15％波形低下 / Amplitude / 70％以下低下 |
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| Research Abstract |
From 2007, the Monitoring Committee of the Japanese Society for Spine Surgery and Related Research conducted a nationwide multi-center study to determine the current situation of intraoperative spinal cord monitoring. A total of 6,887 cases of monitoring were compiled. When dividing the cases into those with MMT reduction of 1 and those with MMT reduction of 2 or more, the group with MMT reduction of 1 (60 muscles altogether) included 16 permanently paralyzed muscles (27%), whereas the group with MMT reduction of 2 or more (43 muscles altogether) had a significantly higher rate of 32 permanently paralyzed muscles (74%). (p<.005)
In the group with MMT reduction of 5, all the 12 muscles had permanent paralysis lasting three months or more.The relationship between CMAP waveform changes and MMT reduction shows a low correlation, and an intraoperative amplitude drop to 25% or less of the control waveform amplitude suggests MMT reduction of 2 or more.
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