Development of a new method for controling longitudinal bone growth by continuous local infusion into the epiphysis
| Project/Area Number |
24791549
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthopaedic surgery
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| Research Institution | The University of Tokushima |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 軟骨 / 骨形成 |
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| Outline of Final Research Achievements |
The goal of our study is to establish the drug delivery system using local infusion into the epiphysis. Limb length discrepancy was treated with surgery using external fixation and osteotomy. Although limb lengthening resulted in good in clinical, many problems remain such as a long hospitalization.
In this study, we improved the drug delivery system using a micro-infusion pump instead of a osmotic pump. We also succeeded to suppress the long bone growth. Taken together with our previous study, we can control the long bone growth by a continuous local infusion into the epiphysis.
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Report
(4 results)
Research Products
(3 results)
