| Project/Area Number |
24791630
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | 独立行政法人国立精神・神経医療研究センター |
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Principal Investigator |
MIYAJIMA Moeko 独立行政法人国立精神・神経医療研究センター, 神経研究所 疾病研究第四部, 客員研究員 (90318147)
|
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| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
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| Keywords | 全身麻酔 / 幼弱期暴露 / 障害 / 霊長類 / 全身麻酔薬 |
|---|
| Research Abstract |
Recently it was reported that children who received general anesthesia repeatedly before 4 years were at significantly increased risk of learning disability. Many animal studies have shown that commonly used anesthetic agents have a neurotoxic effect on the developing brain. The purpose of this study is to examine whether general anesthetic causes neuroapoptosis in neonatal marmosets. We observed increased apoptosis not only in the cortex but also in the white matter.
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