| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
We established an experimental rat model similar to the actual nerve-sparing radical prostatectomy (RP) in patients. A tissue sealing sheet has recently been used for intraoperative bleeding in RP. However, the efficacy of tissue sealing sheet for erectile function following nerve-sparing RP remains unclear. We evaluated the effect of the tissue sealing sheet on nerve injury-related erectile dysfunction (ED). The tissue sealing sheet attenuated ED following cavernous nerve dissection in a rat model of nerve-sparing RP. The tissue sealing sheet may thus represent a useful therapeutic approach to improve ED occurring after nerve-sparing RP, and the prospective clinical trial is on going to elucidate the effect of the tissue sealing sheet.
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