Erectile dysfunction after pelvic surgery
Project/Area Number |
24791632
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Urology
|
Research Institution | Tohoku University |
Principal Investigator |
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 勃起障害 / 骨盤内手術 |
Outline of Final Research Achievements |
We established an experimental rat model similar to the actual nerve-sparing radical prostatectomy (RP) in patients. A tissue sealing sheet has recently been used for intraoperative bleeding in RP. However, the efficacy of tissue sealing sheet for erectile function following nerve-sparing RP remains unclear. We evaluated the effect of the tissue sealing sheet on nerve injury-related erectile dysfunction (ED). The tissue sealing sheet attenuated ED following cavernous nerve dissection in a rat model of nerve-sparing RP. The tissue sealing sheet may thus represent a useful therapeutic approach to improve ED occurring after nerve-sparing RP, and the prospective clinical trial is on going to elucidate the effect of the tissue sealing sheet.
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Report
(4 results)
Research Products
(7 results)