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Development of intraoperative navigation system for robot-assisted radical prostatectomy utilizing two-photon microscope

Research Project

Project/Area Number 24791647
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Urology
Research InstitutionKobe University

Principal Investigator

HINATA Nobuyuki  神戸大学, 医学(系)研究科(研究院), 講師 (10598816)

Research Collaborator TAKENAKA Atsushi   (50368669)
Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords骨盤内神経 / ロボット支援手術 / 自律神経 / 根治的前立腺全摘除術 / 術中ナビゲーション / 前立腺癌 / 機能温存 / 骨盤内神経解剖学 / 二光子励起蛍光顕微鏡
Research Abstract

The aim of the present study was to analyze a feasibility of utilizing two-photon microscope in the intraoperative navigation system for robot-assisted radical prostatectomy. Male rats were observed and sacrificed, then the tissues were stained using H-E staining, Masson-Trichrome staining, anti-thyroxin Hydroxidase immunostaining, and anti-nNOS immunostaining. Although it was difficult to set suitable wavelength to observe the autonomic nerves in the rat pelvis, we obtained ideas from the present study and reported some observations about neuroanatomy for pelvic organs and intraoperative imaging systems derived from the present study.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (3 results)

All 2013 Other

All Journal Article (3 results) (of which Peer Reviewed: 2 results)

  • [Journal Article] Coexistence of Elastic Fibers with Hyaluronic Acid in the Human Urethral Sphincter Complex: A Histological Study2013

    • Author(s)
      Hinata N, Murakami G, Abe S, Shibata S, Morizane S, Honda M, Isoyama T, Sejima T, Takenaka A
    • Journal Title

      Journal of Urology

      Volume: 190 Issue: 4 Pages: 1313-1319

    • DOI

      10.1016/j.juro.2013.04.023

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Dry box training with three-dimensional vision for the assistant surgeon in robot-assisted urological surgery.2013

    • Author(s)
      Hinata N, Iwamoto H, Morizane S, Hikita K, Yao A, Muraoka K, Honda M, Isoyama T, Sejima T, Takenaka A.
    • Journal Title

      Int J Urol.

      Volume: ? Issue: 10 Pages: 1037-1041

    • DOI

      10.1111/iju.12101

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Dry box training with three-dimensional vision for the assistant surgeon in robot-assisted urological surgery

    • Author(s)
      Hinata N, Iwamoto H, Morizane S, Hikita K, Yao A, Muraoka K, Honda M, Isoyama T, Sejima T, Takenaka A
    • Related Report
      2013 Final Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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