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Effects of arterial ischemia and venous congestion on the rat testis

Research Project

Project/Area Number 24791673
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Urology
Research InstitutionTokyo Medical University

Principal Investigator

HIRAI Shuichi  東京医科大学, 医学部, 講師 (70516054)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords精巣 / 虚血 / 鬱血 / 動脈性虚血 / 静脈性鬱血
Research Abstract

This study aimed to clarify different effects of testicular arterial ischemia and venous congestion. Macroscopic examination indicated that the testes of the AI group had turned white, whereas the testes of the VC group had turned reddish-black and swollen. However, histological evaluation indicated that the number of dead germ cells increased in seminiferous tubules more in the AI group than in the VC group Our results suggest that when testicular blood flows are disturbed, macroscopic findings are unsuitable for predicting testicular function prognosis.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (15 results)

All 2013 2012

All Journal Article (10 results) (of which Peer Reviewed: 10 results) Presentation (5 results)

  • [Journal Article] Effects on the Local Immunity in the Testis by Exposure to Di-(2-ethylhexyl) Phthalate (DEHP) in Mice2013

    • Author(s)
      Kitaoka M, Hirai S, Terayama H, Naito M, Qu N, Hatayama N, Miyaso H, Matsuno Y, Komiyama M, Itoh M, Mori C
    • Journal Title

      J Reprod Dev

      Volume: (In press)

    • NAID

      130003361051

    • URL

      https://www.jstage.jst.go.jp/article/jrd/advpub/0/advpub_2012-180/_pdf

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Serum autoantibodies in mice immunized with syngeneic testicular germ cells alone.2013

    • Author(s)
      Hirai S, Naito M, Terayama H, Hatayama N, Qu N, Musha M, Itoh M.
    • Journal Title

      Am J Reprod Immunol

      Volume: 70 Issue: 6 Pages: 509-517

    • DOI

      10.1111/aji.12145

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Lymphangiogenesis in chronic inflammation in the testis.2013

    • Author(s)
      Hirai S, Naito M, Terayama H, Qu N, Kuerban M, Musha M, Itoh M.
    • Journal Title

      Andrology

      Volume: 1(1) Issue: 1 Pages: 147-154

    • DOI

      10.1111/j.2047-2927.2012.00015.x

    • Related Report
      2013 Annual Research Report 2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] The effects of adjuvants on autoimmune responses against testicular antigens in mice2013

    • Author(s)
      Musha M, Hirai S, Naito M, Terayama H, Qu N, Hatayama N, Itoh M
    • Journal Title

      J Reprod Dev

      Volume: 59(2) Pages: 139-44

    • NAID

      10031170771

    • URL

      https://www.jstage.jst.go.jp/article/jrd/59/2/59_2012-121/_pdf

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nine renal arteries in a Japanese female cadaver.2013

    • Author(s)
      Hirai S, Honma S, Naito M, Terayama H, Kawata S, Itoh M.
    • Journal Title

      Anat Sci Int.

      Volume: 88(2) Issue: 2 Pages: 118-21

    • DOI

      10.1007/s12565-012-0161-y

    • NAID

      10031167956

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effects of adjuvants on autoimmune responses against testicular antigens in mice.2013

    • Author(s)
      Musha M, Hirai S, Naito M, Terayama H, Qu N, Hatayama N, Itoh M.
    • Journal Title

      J Reprod Dev.

      Volume: 59(2) Pages: 139-44

    • NAID

      10031170771

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nine renal arteries in a Japanese female cadaver.2013

    • Author(s)
      Hirai S, Honma S, Naito M, Terayama H, Kawata S, Itoh M.
    • Journal Title

      Anatomical Science International

      Volume: 88 Pages: 118-121

    • NAID

      10031167956

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effect of a magnetic field on Drosophila under supercooled conditions2012

    • Author(s)
      Naito M, Hirai S, Mihara M, Terayama H, Hatayama N, Hayashi S, Matsushita M, Itoh M
    • Journal Title

      PLoS One

      Volume: 7(12) Issue: 12 Pages: e51902-e51902

    • DOI

      10.1371/journal.pone.0051902

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The origin of lymphatic capillaries in murine testes2012

    • Author(s)
      Hirai S, Naito M, Terayama H, Qu N, Kuerban M, Musha M, Ikeda A, Miura M, Itoh M
    • Journal Title

      J Androl

      Volume: 33(4) Issue: 4 Pages: 745-51

    • DOI

      10.2164/jandrol.111.015156

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Testicular autoimmunity in men-its suggestion that a Japanese pathologist left2012

    • Author(s)
      Hirai S, Itoh M
    • Journal Title

      Reproductive Immunology and Biology

      Volume: 27(1) Pages: 7-13

    • NAID

      130004949493

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Presentation] Role of macrophages in newly formed lymphatic vessels in the testis2013

    • Author(s)
      平井宗一
    • Organizer
      The International Society for Immunology of Reproduction
    • Place of Presentation
      Boston
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] 精巣における虚血障害および鬱血障害の違い2013

    • Author(s)
      平井宗一
    • Organizer
      第118回日本解剖学会・全国学術集会
    • Place of Presentation
      香川
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] スンクス雄性生殖器の構造2012

    • Author(s)
      平井宗一
    • Organizer
      第6回スンクス研究会
    • Place of Presentation
      山梨
    • Year and Date
      2012-03-26
    • Related Report
      2013 Final Research Report
  • [Presentation] Rare two cases of multiple renal arteries2012

    • Author(s)
      平井宗一
    • Organizer
      1st congress of Asian Association of Clinical Anatomists
    • Place of Presentation
      Korea
    • Related Report
      2013 Final Research Report
  • [Presentation] 重複腎動脈の解剖学的考察2012

    • Author(s)
      平井宗一
    • Organizer
      第117回日本解剖学会・全国学術集会
    • Place of Presentation
      山梨
    • Related Report
      2013 Final Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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