Placental DNA methylation pattern in preeclampsia
Project/Area Number |
24791723
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Obstetrics and gynecology
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Research Institution | Showa University |
Principal Investigator |
KOIDE Keiko 昭和大学, 医学部, 助教 (90384437)
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Research Collaborator |
SEKIZAWA Akihiko 昭和大学, 医学部, 教授 (10245839)
TAKENAKA Shin 昭和大学, 医学部, 助教 (60515211)
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Project Period (FY) |
2012-04-01 – 2014-03-31
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Project Status |
Completed (Fiscal Year 2013)
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Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | DNAメチル化 / 妊娠高血圧腎症 / なし |
Research Abstract |
Normal placentation and placental development require changes of DNA methylation status in some specific genes and the responsible genes differ with stage in pregnancy. It was suggested that the alterations of villous DNA methylation caused between 6 to 11 weeks were associated with the pathogenesis of preeclampsia.
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Report
(3 results)
Research Products
(11 results)
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[Presentation] Placental DNA methylation pattern in preeclampsia2013
Author(s)
Keiko Koide, Kyoko Hori, Satoshi Miyagami, Shin Takenaka, Akihiro Kawashima, Hiroshi Chiba, Akihiko Sekizawa
Organizer
International Society For the Study of Hypertesion in Pregnancy World Congress
Place of Presentation
カナダ(ウィスラー)
Year and Date
2013-09-12
Related Report
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