| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
While it is considered that D-amino acids were eliminated from living organisms, various physiological functions of D-amino acids have received a lot of attention in recent years. We discussed the expression of D-aspartic acid in various tissues of the otorhinolaryngological field. D-aspartic acid expressed in palatine tonsils, cholesteatomas, nasal polyps and vocal cord polyps, which are involved in the chronic inflammation. It was revealed the correlation between aging and the expression levels of D-aspartic acid. A different expression pattern was identified in different disease states of palatine tonsils and cholesteatomas, so it was seemed that D-aspartic acid is concerned in the mechanism of disease states.
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