| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
We developed the transgenic mice that overexpressed galectin-3 in the thyroid tissue, so that the role of galectin-3 overexpression in the thyroid carcinoma would be elucidated. We removed the thyroids of the transgenic mice at the age of 3-month and observed them under a microscope. There were no carcinomas or abnormalities in the thyroid tissue. This result indicates that overexpression of galectin-3 would not be the important factor for carcinogenesis but arise on the result after thyroid carcinoma is occurred, whereas we cannot conclude it with relatively short observation period.
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