Analysis of invasion and metastasis system in pharyngeal carcinoma by epitherial cell polar factor and hippo signal pathway
| Project/Area Number |
24791795
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
KONDO Atsushi 札幌医科大学, 医学部, 講師 (40457718)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 咽頭癌 / 細胞極性 / タイト結合 / 接着分子 |
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| Research Abstract |
Recently, it is reported that JAM-A is closely associated with invasion and metastasis of cancers such as breast cancer, esophageal cancer. However little is known about the role of JAM-A in invasion and metastasis of head and neck squamous cell carcinoma. Head and neck squamous cell carcinoma tissues obtained by surgery from patients with head and neck carcinoma.To investigate expression and distribution of JAM-A, we performed real-time PCR, immunofluorescence staining by using frozen sections and immunohistochemistry by using paraffin sections. JAM-A was highly expressed in head and neck squamous cell carcinoma
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Report
(3 results)
Research Products
(32 results)
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[Journal Article] Analysis and results of Ku and XRCC4 expression in hypopharyngeal cancer tissues treated with chemoradiotherapy2012
Author(s)
Hayashi J, Sakata KI, Someya M, Matsumoto Y, Satoh M, Nakata K, Hori M, Takagi M, Kondoh A, Himi T, Hareyama M
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Journal Title
Oncol Lett
Volume: 4
Pages: 151-155
URL
Related Report
Peer Reviewed
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[Journal Article] Malignant melanoma of the head and neck : A multi-institutional retrospective analysis of cases in Northern Japan2012
Author(s)
Shiga K, Ogawa T, Kobayashi T, Ueda S, Kondo A, Nanba A, Kuwashima S, Asada Y, Suzuki S, Nagahashi T, Takahashi M, Suzuki M, Ishida A, Watanabe K, Harabuchi Y, Himi T, Shinkawa H, Sato H, Saijyo S, Fukuda S, Tanaka K, Ishikawa K, Omori K, Aoyagi M, Hashimoto S
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Journal Title
Head Neck
Volume: (in press)
Issue: 11
Pages: 1537-1541
DOI
Related Report
Peer Reviewed
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[Journal Article] Analysis and results of Ku and XRCC4 expression in hypopharyngeal cancer tissues treated with chemoradiotherapy.2012
Author(s)
Hayashi J, Sakata KI, Someya M, Matsumoto Y, Satoh M, Nakata K, Hori M, Takagi M, Kondoh A, Himi T, Hareyama M
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Journal Title
Oncol Lett
Volume: 4(1)
Pages: 151-155
Related Report
Peer Reviewed
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