| Project/Area Number |
24791806
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
|
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| Research Institution | Keio University |
|---|
Principal Investigator |
SATO Yoichiro 慶應義塾大学, 医学部, 助教 (40624440)
|
|---|
| Research Collaborator |
IMANISHI Yorihisa 慶應義塾大学, 医学部, 講師 (80255538)
WATANABE Yoshihiro 慶應義塾大学, 医学部, 助教 (30445374)
|
|---|
| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Keywords | 頭頸部癌 / 上皮間葉移行 / 癌幹細胞 / 癌転移 / 分子標的治療 / 頭頸部扁平上皮癌（HNSCC） / EMT（上皮-間葉移行） |
|---|
| Research Abstract |
Oct3/4 and Nanog expression putative cancer stem cells with enhanced cell migration and invasion, and then was thought to induce EMT, experiencing the metastasis in head and neck squamous cell carcinoma. That could lead to new treatment for targeting cancer stem cells, such as oct3/4, Nanog recurrence and metastasis inhibition was suggested.
|
