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The impact of the bony immunological reaction on the chronic rhinosinusitis

Research Project

Project/Area Number 24791812
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Otorhinolaryngology
Research InstitutionJikei University School of Medicine

Principal Investigator

OKUSHI Tetsushi  東京慈恵会医科大学, 医学部, 講師 (50317939)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords医療 / 鼻科学 / 慢性副鼻腔炎 / 骨免疫応答 / 骨応答 / 粘膜 / 骨膜 / 術後性上顎嚢胞
Research Abstract

Medical and surgical therapy for chronic rhinosinusitis and cystic lesions are worldwide standardized. However recurrence after these therapy were observed in some patients. Interactions between bony tissue and mucosa were investigated to reveal one of factors of refractory situations.
Bony lesions were observed in a considerable number of chronic rhino sinusitis patients, and especially in revision surgery cases. Almost of odontogenic chronic rhinosinusitis patients showed severe bony lesions, and postoperative persisting mucosal thickness was observed. Relationship between bony thickness and surgical outcome was observed in postoperative maxillary cyst patients. Co- influence between the bony lesions and muss was presumed in some way.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (4 results)

All 2014 2013 2012

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (3 results)

  • [Journal Article] A modified Lund-Machay system for radiological evaluation of chronic rhinosinusits2013

    • Author(s)
      Tetsushi Okushi
    • Journal Title

      Auris Nasus Larynx

      Volume: 40(6) Issue: 6 Pages: 548-53

    • DOI

      10.1016/j.anl.2013.04.010

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] 術後性上顎嚢胞に対する粘骨膜弁の応用について2014

    • Author(s)
      大櫛哲史
    • Organizer
      第113回日本耳鼻咽喉科学会
    • Place of Presentation
      新潟
    • Year and Date
      2014-05-10
    • Related Report
      2013 Final Research Report
  • [Presentation] Endoscopic endonasal surgery of postoperative maxillary cysts using mucoperiosteal flap technique2013

    • Author(s)
      Tetsushi Okushi
    • Organizer
      World Congress of the International Federation of Oto-Rhino-Laryngological Societies
    • Place of Presentation
      韓国 ソウル
    • Related Report
      2012 Research-status Report
  • [Presentation] Endoscopic endonasal surgery of postoperative maxillary cysts using mucoperiosteal flap technique2012

    • Author(s)
      Tetsushi Okushi
    • Organizer
      International Symposium on Infection and Allergy of the Nose
    • Place of Presentation
      フランス / トゥールーズ
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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