Develop ment of simple and easy, highly precise osteoporotic screenign to evaluate a fracture risk from skin

• Project/Area Number: 24792014
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Pathobiological dentistry/Dental radiology
• Research Institution: Kanagawa Dental College
• Principal Investigator: KOZAI Yusuke 神奈川歯科大学, 歯学研究科(研究院), 助教 (80550855)
• Project Period (FY): 2012-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: 骨粗鬆症 / 骨密度測定 / 皮膚 / 骨構造

Research Abstract

We researched that for establishment of the technique to estimate a fracture risk from a sulcus cutis structure using the skin quality analysis device which we developed newly.As a result, we made clear that the skin quality analysis device could detect deterioration of the skin due to the aging sensitively.
Also, it was found that there was an association between a bone quality and the skin quality and the deterioration of bone by comparing the results of the skin quality analysis.It found that we might infer the deterioration of bone due to osteoporosis from skin quality analysis.

Research Products

• [Journal Article] Effects ofβ -cryptoxanthin on bone-formation parameters in the distal femoral epiphysis of ovariectomized mice (2014)
  • Author(s): Iino M, Kozai Y, Kawamata R, Wakao H, Sakurai T, Kashima I
  • Journal Title: Oral Radiology Volume: 30巻 Issue: 1 Pages: 1-8
  • DOI: 10.1007/s11282-013-0131-7
  • Peer Reviewed
• [Journal Article] Inhibitory effect of fermented soy product from lactic acid bacteria (PS-B1) on deterioration of bone mass and quality in ovariectomized mice (2014)
  • Author(s): Miura T, Kozai Y, Kawamata R, Wakao H, Sakurai T, Kashima I
  • Journal Title: Oral Radiol Volume: 30巻 Issue: 1 Pages: 45-52
  • DOI: 10.1007/s11282-013-0143-3
  • Peer Reviewed
• [Journal Article] The effect of simvastatin-loaded polymeric microspheres in a critical size bone defect in the rabbit calvaria (2014)
  • Author(s): Naito Y, Terukina T, Galli S, Kozai Y, Vandeweghe S, Tagami T, Ozeki T, Ichikawa T, Coelho PG, Jimbo R
  • Journal Title: Int J Pharm Volume: 461巻 Issue: 1-2 Pages: 157-62
  • DOI: 10.1016/j.ijpharm.2013.11.046
  • Peer Reviewed
• [Journal Article] The influence of nano hydroxyapatite coating on osseointegration after extended healing periods (2013)
  • Author(s): Bryngton Ms, Hayashi M, Kozai Y, Vandeweghe S, andersson M, Wennerberg A, Jimbo R
  • Journal Title: Dental Materials Volume: 29巻 Issue: 5 Pages: 514-520
  • DOI: 10.1016/j.dental.2013.02.004
  • Peer Reviewed
• [Journal Article] Bone apposition to laminin-1 coated implants : histologic and 3D evaluation (2013)
  • Author(s): Bougas K, Jimbo R, Vandeweghe S, Hayashi M, Bryington M, Kozai Y, Schwartz-Filho HO, Tovar N, Adolfsson E, Ono D, Coelho PG, Wennerberg A
  • Journal Title: International Journal of Oral Maxillofacial Surgery Volume: 42巻 Issue: 5 Pages: 677-682
  • DOI: 10.1016/j.ijom.2012.11.008
  • Peer Reviewed
• [Presentation] 携帯端末を利用した肌質評価方法の提案 (2013)
  • Author(s): 香西雄介
  • Organizer: NPO 法人広域連携医療福祉システム支援機構講習会:最近の美容皮膚科学の現状と今後の展望-医工連携を目指して
• [Presentation] 携帯端末を利用した肌質評価方法の提案 (2013)
  • Author(s): 香西雄介
  • Organizer: NPO法人 広域連携医療福祉システム支援機構 講習会：最近の美容皮膚科学の現状と今後の展望―医工連携を目指して―
  • Place of Presentation: KGU関内メディアセンター
  • Invited
• [Presentation] 閉経周辺期における画像工学的骨質変化検出法の検討 (2012)
  • Author(s): 印南 永, 香西雄介, 川股亮太, 櫻井 孝
  • Organizer: 日本歯科放射線学会第53回総会・学術大会
• [Remarks] lab.kdu.ac.jp
  • URL: http://www.labs.kdu.ac.jp/radiol/skin.html
• [Remarks] labs.kdu.ac.jp
  • URL: http://www.labs.kdu.ac.jp/radiol/skin.html