The effects of gene associated with sucrose phosphotransferase system on biofilm formation of Streptococcus mutans

Research Project

Project/Area Number	24792027
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Conservative dentistry
Research Institution	The University of Tokushima
Principal Investigator	KIMURA Tomoko 徳島大学, ヘルスバイオサイエンス研究部, 助教 (20581367)
Project Period (FY)	2012-04-01 – 2014-03-31
Project Status	Completed (Fiscal Year 2013)
Budget Amount *help	¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000) Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000) Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords	歯学 / う蝕 / 細菌 / 遺伝子 / バイオフィルム
Research Abstract	The aim of this study was to investigate the involvement of scrA gene deeply related to the acidogenic activity in cariogenic bacterium in the initial adhesion and glucan synthesis by Streptococcus mutans. ELISA assay revealed that scrA gene had an effect on the initial adhesion. The measurement of glucan demonstrated that scrA gene involved in the synthesis of glucan, a component of biofilm.

Report

(3 results)