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Development of long-term used oral care materials including nano-bubble of crude drug component

Research Project

Project/Area Number 24792052
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Prosthetic dentistry
Research InstitutionTohoku University

Principal Investigator

HONG Guang  東北大学, 歯学研究科(研究院), 准教授 (70363083)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsナノバブル / 生薬 / AQP5 / 口腔ケア / 歯科補綴学
Outline of Final Research Achievements

The purpose of this study was to development of oral care material include crude drug which can prevention and treatment of denture stomatitis, dry-mouth and so on. In this study we investigated the influence of component on the mechanical properties and angiogenesis of oral care materials. The results suggest that the the durability of oral care materials can improve by combination of components of materials from viewpoint of viscoelasticity; and the angiogenesis was greatly influenced by the components of oral care materials. From this results, it is possible to produced crude drug active ingredient formulated oral care materials. It is indicated that the denture stomatitis and dry mouth can prevented and treated by this materials.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (15 results)

All 2015 2014 2013 2012 Other

All Journal Article (8 results) (of which Peer Reviewed: 8 results,  Open Access: 2 results,  Acknowledgement Compliant: 1 results) Presentation (7 results) (of which Invited: 4 results)

  • [Journal Article] Evaluation of the efficiency of denture cleaners for removing denture adhesives2015

    • Author(s)
      Harada-Hada K, Hong G, Abekura-H, Murata H
    • Journal Title

      Gerodontology

      Volume: 印刷中 Issue: 4 Pages: 453-460

    • DOI

      10.1111/ger.12183

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The adhesive strength and initial viscosity of denture adhesives.2014

    • Author(s)
      JM Han, G Hong*, MS Dilinuer, H Lin, G Zheng, XZ Wang, K Sasaki.
    • Journal Title

      Acta Odontol Scand

      Volume: 72 Pages: 839-845

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Influence of composition on the adhesive strength and initial viscosity of denture adhesives.2014

    • Author(s)
      JM Han, G Hong*, K Hayashida, T Maeda, H Murata, K Sasaki
    • Journal Title

      Dent Mater J

      Volume: 33 Pages: 98-103

    • NAID

      130003394945

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Influence of chlorine dioxide on the physical properties of denture base materials.2013

    • Author(s)
      T Shinhara, T Maeda, G Hong*, H Nishizaki, J Okazaki.
    • Journal Title

      Asian Pac J Dent

      Volume: 13 Pages: 27-35

    • NAID

      40019956569

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] 義歯洗浄剤が歯科用金属材料の色調安定性に及ぼす影響.2013

    • Author(s)
      新原拓也,洪 光*,前田武志,佐野有哉,佐々木啓一,岡崎定司.
    • Journal Title

      日本歯科理工学会誌

      Volume: 32 Pages: 220-225

    • NAID

      110009611707

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Durability of peel bond of resilient denture liners to acrylic denture base resin.2012

    • Author(s)
      T. Maeda, G. Hong*, S. Sadamori, T. Hamada, Y. Akagawa.
    • Journal Title

      J Prosthodont Res

      Volume: 56 Pages: 136-141

    • NAID

      130004546632

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] The dynamic viscoelasticity and plasticizer leachability of tissue conditioners.2012

    • Author(s)
      G. Hong*, T. Maeda, H. Murata, K. Sasaki.
    • Journal Title

      Gerodontology

      Volume: 29 Pages: 284-291

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effect of maching adhesives and composite resins on microleakage.2012

    • Author(s)
      J. Han, R. Zheng, H. Lin, G. Zheng*, G. Hong.
    • Journal Title

      J Mode Stomat

      Volume: 26 Pages: 312-314

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] Development of functionality dental materials.2014

    • Author(s)
      G Hong
    • Organizer
      The 3rd International Symposium on Dental Implantology and Biomaterials of West Coast Strait
    • Place of Presentation
      Fuzhou, China
    • Year and Date
      2014-11-24
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] The latest progress of development of functionality dental materials.2014

    • Author(s)
      G Hong
    • Organizer
      9th Congress of Chinese Dental Materials
    • Place of Presentation
      Dalian, China
    • Year and Date
      2014-10-10 – 2014-10-11
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Influence of soft acrylic resin materials on angiogenesis in vitro.2014

    • Author(s)
      G Hong, WQ Wang, Y Shimizu, JM Han, K Sasaki.
    • Organizer
      92nd General Session of IADR
    • Place of Presentation
      Cape Town, South Africa
    • Year and Date
      2014-06-24 – 2014-06-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] 音叉振動式粘度計を用いた口腔湿潤材の粘度評価2012

    • Author(s)
      洪 光,王 維奇,金高弘恭,佐々木啓一
    • Organizer
      第22回日本歯科医学会総会
    • Place of Presentation
      インデックス大阪
    • Related Report
      2012 Research-status Report
  • [Presentation] Development of functionality dental materials for prosthodontics.

    • Author(s)
      G. Hong
    • Organizer
      Peking-Tohoku Dental Symposium
    • Place of Presentation
      Peking University School of Stomatology
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 粘膜調整材が口腔粘膜内の血管新生に及ぼす影響に関する基礎的研究

    • Author(s)
      王 維奇,洪 光,清水良央,佐々木啓一
    • Organizer
      第62回日本歯科理工学会学術講演会
    • Place of Presentation
      日本大学新潟生命歯学部
    • Related Report
      2013 Research-status Report
  • [Presentation] Development of high biological safety tissue conditioners.

    • Author(s)
      G. Hong
    • Organizer
      International Symposium on Dental Material and Tissue Regeneration
    • Place of Presentation
      Fujian Medical university School of Stomatology
    • Related Report
      2012 Research-status Report
    • Invited

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Published: 2013-05-31   Modified: 2019-07-29  

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