A study on early diagnosis of residual ridge resorption beneath the denture base by using NaF-PET

• Project/Area Number: 24792057
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Prosthetic dentistry
• Research Institution: Tohoku University
• Principal Investigator: SUENAGA Hanako 東北大学, 大学病院, 助教 (00508939)
• Project Period (FY): 2012-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 義歯床下圧力動態 / 生体内測定 / NaF-PET / 骨代謝定量 / ヒト / 有床義歯 / メカノバイオロジー / 骨代謝 / RPD / 骨代謝動態 / 生体内床下圧測定

Research Abstract

This study aimed to describe the time course of the bone metabolism at the residual ridge beneath the denture following denture use by NaF-PET. Three subjects, who had a free-end edentulous mandible, were treated with a denture replacing the edentulous region of the dental arch. NaF-PET/CT scanning was performed at baseline, 4-6 and 13 weeks after denture use. A volume of interest (VOI) was placed on their mandibles at the edentulous region beneath the denture. CT value and mean standardized uptake value (SUV) of the VOI were calculated. The SUVs of each VOI significantly increased at 4–6 weeks after denture use and then decreased at 13 weeks in all three subjects (P

Research Products

• [Journal Article] Different of occlusal rest designs on pressure distribution beneath the denture base of distal extension RPDs - A Preliminary in vivo study (2014)
  • Author(s): Suenaga H, Kubo K, Hosokawa R, Kuriyagawa T, Sasaki K
  • Journal Title: International Journal of Prosthodontices Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Effects of occlusal rest design on pressure distribution beneath the denture base of distal extension RPD; An in vivo study (2014)
  • Author(s): Suenaga H, Kubo K, Hosokawa R, Kuriyagawa T, Sasaki K
  • Journal Title: International Journal of Prosthodontics Volume: in press
  • Peer Reviewed
• [Journal Article] Bone response to immediate loading through titanium implants with different surface roughness in rats (2013)
  • Author(s): Sato N, Kuwana T, Yamamoto M, Suenaga H, Anada T, Koyama S, Suzuki O, Sasaki K
  • Journal Title: Odontology Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Bone response to immediate loading through titanium implants with different surface roughness in rats (2013)
  • Author(s): Sato N, Kuwana T, Yamamoto M, Suenaga H, Anada T, Koyama S, Suzuki O, Sasaki K.
  • Journal Title: Odontology Volume: - Issue: 2 Pages: 1-10
  • DOI: 10.1007/s10266-013-0107-4
  • Peer Reviewed
• [Journal Article] Time course of bone metabolism at the residual ridge beneath dentures observed using ^<18>F-fluoride positron emission computerized-tomography/computed tomography (PET/CT) (2012)
  • Author(s): Suenaga H, Yokoyama M, Yamaguchi K, Sasaki K
  • Journal Title: Ann Nucl Med Volume: 26 Issue: 10 Pages: 817-22
  • DOI: 10.1007/s12149-012-0648-6
  • NAID: 10031143987
  • Peer Reviewed
• [Presentation] Analysis of mechanobiological bone reaction beneath the denture by using PET and FEM (2013)
  • Author(s): Suenaga H
  • Organizer: Sydney-Tohoku Dental Symposium
  • Place of Presentation: オーストラリア・シドニー大学
• [Presentation] NaF-PETを用いた義歯床下のメカノバイオロジカルな骨代謝活性に関する研究 (2012)
  • Author(s): 末永華子, 横山政宣, 依田信裕, 小川徹, 山口慶一郎, 佐々木啓一
  • Organizer: 第22回日本歯科医学会総会
  • Place of Presentation: 大阪