| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
The purpose of this study was to identify the biological markers that are involved in the onset and progression of peri-implantitis. First, we developed a clinical examination protocol by referring to the previous reports and investigated the prospective study for the initial peri-implantitis patient using the developed protocol. The subject of this study was five and, basic information of subjects was shown below, average age: 71.0 ± 4.6 years, average number of implants per patient : 4.8 ± 2.4, average number of implant with peri-implantitis：1.4 ± 0.5) . To identify the biological markers, gingival crevicular fluids around the oral implant and natural tooth were collected by using the paper points. ,The adequate amount of bacterial DNA could be collected for 16S rRNA sequencing using this protocol.
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