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Relationship between Peri-implant Bone Metabolism and immediate Loading using [18F]NaF-PET Image Analyses

Research Project

Project/Area Number 24792130
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Dental engineering/Regenerative dentistry
Research InstitutionTohoku University

Principal Investigator

YAMAMOTO Miou  東北大学, 歯学研究科(研究院), 大学院非常勤講師 (10624827)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsインプラント / 骨代謝 / PET
Research Abstract

CT and [18F]NaF-PET allowed for a precise estimate of bone metabolism, bone density and trabecular bone structure around the dental implants. Histological deta clearly showed osteogenic reaction around the implants, which related bone metabolism and bone density.
Using [18F]NaF-PET, bone metabolism around the implant could be estimated precisely and three-dimensionally. The result suggests the loading effects in early stage on peri-implant bone formation. Comparing with our previous data using Tc99m-MDP bone-scintigraphy, the results of this study showed different manners of bone-metabolism. Those differences might be due to a difference of uptake mechanisms between 2 tracers, namely 18F- and MDP.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (4 results)

All 2013 2012

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (3 results)

  • [Journal Article] Influence of immediate and early loading on bone metabolic activity around dental implants in rat tibiae2013

    • Author(s)
      Yamamoto M, Ogawa T, Yokoyama M, Koyama S, Sasaki K.
    • Journal Title

      Clin Oral Implants Res

      Volume: (印刷中) Issue: 9 Pages: 1084-1090

    • DOI

      10.1111/clr.12218

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Presentation] [^<18F>]NaF-PET Image Analyses Peri-implant Bone Metabolism Elictied by Loading2013

    • Author(s)
      Yutaka Matsuo, Miou Yamamoto, Toru Ogawa, Masayoshi Yokoyama, Keiichi Sasaki
    • Organizer
      7th East Asian Consortium on Biomedical Engineering
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2013 Final Research Report
  • [Presentation] [18F]NaF-PET Image Analyses of Peri-implant Bone Metabolism Elicited by Loading2013

    • Author(s)
      Yutaka Matsuo, Miou Yamamoto, Toru Ogawa, Masayoshi Yokoyama, Keiichi Sasaki
    • Organizer
      7th East Asian Consortium on Biomedical Engineering
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Evaluation of Peri-Implant Bone Metabolism with High-resolution NaF-PET during Mechanical Loading2012

    • Author(s)
      Matsuo Y, Yamamoto M, Ogawa T, Yokoyama M, Sasaki K
    • Organizer
      The 60th Annual Meeting of Japanese Association for Dental Research
    • Place of Presentation
      Niigata, Japan
    • Related Report
      2013 Final Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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