| Project/Area Number |
24792132
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Jichi Medical University (2015)
Tokyo Medical and Dental University (2012-2014) |
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Principal Investigator |
sakuyama aoi 自治医科大学, 医学部, 臨床助教 (10543340)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | bisphosphonate / BRONJ / MRONJ / animal / osteoporosis / implant / mandible / BP / 動物実験 / ウサギ / インプラント / 顎骨壊死 / 骨髄炎 |
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| Outline of Final Research Achievements |
The number of patients of osteoporosis progresses aging is increasing, has been jawbone necrosis are many reports by taking bisphosphonate (less than BP). BP was carried out to study the effects on the implant from the point of view of the bone formation peri-implant.
In the lower limbs and jaw bone, new bone formation on the peri-implant it is different. To clarify the new bone formation, it is necessary to observe the jawbone. In addition, when not being administered a BP agent, active bone formation was observed.After the implant was combined with a bone, as for the BP, a periodic medical examination is important to the implant to have an influence.
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