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The development of novel scaffold with dental implant

Research Project

Project/Area Number 24792162
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Dental engineering/Regenerative dentistry
Research InstitutionOsaka Dental University

Principal Investigator

UEMURA Naoya  大阪歯科大学, 歯学部附属病院, 助教 (50610309)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords再生医療 / 再生
Research Abstract

The aim of this study is to evaluate the bone regeneration ability, as it can become the Trans Sectional Research eventually in bone regeneration medicine for clinical application, which the novel product of the bone substitute material (a-TCP and synthetic collagen and poly lactic acid) was put in the fresh socket with immediate implant after teeth extraction.
In the 24 year, we confirmed that the bone regeneration ability of the novel bone substitute material itself in the rat calvarial defect model. (Already presentation and paper published) In the 25 year, we put the novel bone substitute material in the fresh socket with immediate implant after teeth extraction in the dog mandible defect model to close to the clinical situation. Presently, in the middle of this process, we prepare for conference presentation and publish paper.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (14 results)

All 2014 2013 2012

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (10 results)

  • [Journal Article] Evaluation of Bone Regeneration using Platelet-rich or Platelet-poor Plasma Combined with Autologous Mesenchymal Stem Cells2013

    • Author(s)
      Kenichirou Yasui, Yoshiyuki Arima, Li Peiqi, Tomoko Tokuda, Eiko Azumi, Aki Nishiura, Tomohiko Ito, Yoshiya Hashimoto, Naoya Uemura, Shunsuke Baba, Naoyuki Matsumoto
    • Journal Title

      Journal of Oral Tissue Engineering

      Volume: 11 Pages: 57-66

    • NAID

      130004941099

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of bone regeneration by porous alpha-tricalcium phosphate/atelocollagen sponge composite in rat calvarial defects2013

    • Author(s)
      Arima Y
    • Journal Title

      Orthodontic Waves

      Volume: 72 Issue: 1 Pages: 23-29

    • DOI

      10.1016/j.odw.2012.11.001

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Evaluation of Bone Regeneration by Porous Alpha-tricalciumphosphate/Atelocollagen Sponge Composite in Rat Calvarial Defects2012

    • Author(s)
      Arima Y, Uemura N, Hashimoto Y, Baba S, Matsumoto N
    • Journal Title

      Orthodontic Waves

      Volume: 72 Pages: 23-29

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of Bone Regeneration using Platelet-rich or Platelet-poor Plasma Combined with Autologous Mesenchymal Stem Cells2012

    • Author(s)
      Yasui K, Arima Y, Lee P, Tokuda T, Azumi E, Nishiura A, Ito T, Hashimoto Y, Uemura N, Baba S, Matsumoto N
    • Journal Title

      Journal of Oral Tissue Engineering

      Volume: 11(1) Pages: 57-66

    • NAID

      130004941099

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Presentation] Bone Regeneration by Porous Alpha-Tricalciumphoshate/Synthesized Collagen Composite2014

    • Author(s)
      Uemura N, Hieda A, Hirose T, Kaida K, Ito T, Hashimoto Y, Baba S
    • Organizer
      92th General & Exhibition of IADR
    • Place of Presentation
      Cape Town, South Africa
    • Year and Date
      2014-06-26
    • Related Report
      2013 Final Research Report
  • [Presentation] Bone Regeneration by Porous Alpha-Tricalciumphosphate/Synthesized Collagen Composite2014

    • Author(s)
      Naoya Uemura, Ayato Hieda, Takayuki Hirose, Kouzi Kaida, Tomonori Ito, Yoshiya Hashimoto, Shunsuke Baba
    • Organizer
      92th General Session & Exhibition of IADR
    • Place of Presentation
      Cape Town, South Africa
    • Related Report
      2013 Annual Research Report
  • [Presentation] Alpha-tricalcium phosphate/atelocollagen sponge composite versus autogenous bone for repair of calvarial defects in rat models2013

    • Author(s)
      Lee P, Arima Y, Tokuda T, Ryao T, Nishiura A, Hashimoto Y, Uemura N, Baba S
    • Organizer
      日本矯正歯科学会
    • Place of Presentation
      松本市
    • Year and Date
      2013-10-07
    • Related Report
      2013 Final Research Report
  • [Presentation] 臨床応用に向けた合成高分子材料による歯槽骨再生について2012

    • Author(s)
      上村 直也, 橋本典也, 有馬 良幸, 安井 憲一郎, 馬場 俊輔, 川添 堯彬
    • Organizer
      第22回日本歯科医学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2012-11-09
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] Evaluation of Bone Formation of Combining α-TCP and Atelocollagen by 3D Image Construction2012

    • Author(s)
      Arima Y, Yasui K, Sakamoto F, Uemura N, Hashimoto Y, Baba S, Matsumoto N
    • Organizer
      100th FDI Annual World Dental Congress
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2012-08-29
    • Related Report
      2013 Final Research Report
  • [Presentation] Evaluation of Bone Regeneration of Combining PolyPHG and α-TCP2012

    • Author(s)
      Uemura N, Arima Y, Yasui K, Hashimoto Y, Baba S, Kawazoe T
    • Organizer
      90th General Session & Exhibition of the IADR
    • Place of Presentation
      Iguacu Fall, Brazil
    • Year and Date
      2012-06-21
    • Related Report
      2013 Final Research Report
  • [Presentation] The 3D Image of Bone Formation of Combining Synthesize Collagen Polypeptide and α -TCP2012

    • Author(s)
      Uemura N, Arima Y, Yasui K, Hashimoto Y, BabaS, Kawazoe T
    • Organizer
      2012 Sino-Japan Dental Conference
    • Place of Presentation
      Chengdu China
    • Year and Date
      2012-04-26
    • Related Report
      2013 Final Research Report
  • [Presentation] The 3D image of bone formation of combining synthesize collagen polypeptide and α-TCP2012

    • Author(s)
      Uemura N, Arima Y, Yasui K, Hashimoto Y, Baba S, Kawazoe T
    • Organizer
      2012 Sino-Japan Dental Conference
    • Place of Presentation
      Chengdu China
    • Related Report
      2012 Research-status Report
  • [Presentation] Evaluation of bone regeneration of combining PolyPHG and α-TCP2012

    • Author(s)
      Uemura N, Arima Y, Yasui K, Hashimoto Y, Baba S, Kawazoe T
    • Organizer
      90th General Session & Exhibition of the IADR
    • Place of Presentation
      Iguacu Fall, Brazil
    • Related Report
      2012 Research-status Report
  • [Presentation] Evaluation of bone formation of combining α-TCP and atelocollagen by 3D image construction2012

    • Author(s)
      Arima Y, Yasui K, Sakamoto F, Uemura N, Hashimoto Y, Baba S, Matsumoto N
    • Organizer
      100th FDI Annual World Dental Congress
    • Place of Presentation
      Hong Kong
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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