Establishment of gene expression profile of palatal elevation

• Project/Area Number: 24792233
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Surgical dentistry
• Research Institution: Kyushu University
• Principal Investigator: MATSUMURA Kaori 九州大学, 大学病院, その他 (20615794)
• Project Period (FY): 2012-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2012: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
• Keywords: 口蓋裂 / 口蓋突起挙上 / 遺伝子発現 / 口唇裂口蓋裂 / 網羅的遺伝子発現解析 / 国際情報交換

Research Abstract

The experiment was performed to clarify the molecular mechanism of palatal elevation for clinical treatment of cleft palate. Gene expression profile of palatal process before and after elevation was established, and some of genes that could be related to palatal elevation were identified.

Research Products

• [Presentation] Three-dimensional evaluation of postoperative bone resorption after secondary bone grafting (2013)
  • Author(s): Kaori Matsumura, Masaaki Sasaguri, Shinsaku, Arai, Takeshi Mitsuyasu, Seiji Nakamura
  • Organizer: 21st International Congress on Oral and Maxillofacial Surgery
  • Place of Presentation: Barcelona, Spain
  • Year and Date: 2013-10-21
• [Presentation] 当院における口蓋裂クリティカルパスの評価 (2013)
  • Author(s): 新井伸作, 笹栗正明, 窪田泰孝, 光安岳志, 松村香織, 中村誠司
  • Organizer: 第37回日本口蓋裂学会総会・学術大会
  • Place of Presentation: 佐賀
  • Year and Date: 2013-05-30
• [Presentation] 九州大学病院口唇口蓋裂クリニックにおける診療体系 (2013)
  • Author(s): 笹栗正明, 鈴木 陽, 窪田泰孝, 光安岳志, 長谷川幸代, 新井伸作, 松村香織, 森 悦秀, 中村誠司
  • Organizer: 第36回日本口蓋裂学会総会・学術大会
  • Place of Presentation: 新潟
  • Year and Date: 2013-05-26
• [Presentation] Microarray analysis of global gene expression during palatal elevation (2013)
  • Author(s): Kaori Matsumura, Masaaki Sasaguri, Shinsaku Arai, Seiji Nakamura
  • Organizer: 12th International Congress on Cleft Lip/Palate and Related Craniofacial Anomalies
  • Place of Presentation: Florida, USA
  • Year and Date: 2013-05-05
• [Presentation] Effects of intravelar veloplasty in re-pushback palatoplasty (2013)
  • Author(s): Masaaki Sasaguri, Shinsaku Arai, Sachiyo Hasegawa, Kaori Matsumura, Takeshi Mitsuyasu, Norifumi Nakamura Seiji Nakamura, Yuko Ogata
  • Organizer: 12th International Congress on Cleft Lip/Palate and Related Craniofacial Anomalies
  • Place of Presentation: Florida, USA
  • Year and Date: 2013-05-05
• [Presentation] Microarray analysis of global gene expression (2013)
  • Author(s): Kaori Matsumura, Masaaki Sasaguri, Takeshi Mitsuyasu, Shinsaku Arai, Tomomi Tsujiguchi, Seiji Nakamura
  • Organizer: 12th International Congress on Cleft Lip/Palate and Related Craniofacial Anomalies
  • Place of Presentation: アメリカ合衆国 フロリダ州
  • Invited
• [Presentation] Three-dimensional evaluation of postoperative bone resorption after secondary bone grafting (2013)
  • Author(s): Kaori Matsumura, Masaaki Sasaguri, Shinsaku Arai, Takeshi Mitsuyasu, Tomomi Tsujiguchi, Seiji Nakamura
  • Organizer: 21st International conference on oral and maxillofacial surgery
  • Place of Presentation: スペイン バルセロナ
• [Presentation] 多発奇形症候群における口唇口蓋裂の治療について (2012)
  • Author(s): 光安岳志, 笹栗正明, 大部一成, 新井伸作, 松村香織, 中村誠司
  • Organizer: 第24回日本小児口腔外科学会総会・学術大会
  • Place of Presentation: 愛知
  • Year and Date: 2012-11-24
• [Presentation] A case of Aicardi syndrome (2012)
  • Author(s): Kaori Matsumura, Masaaki Sasaguri, Shinsaku Arai, Seiji Nakamura
  • Organizer: 10th Congress of Oral and Maxillofacial Surgery
  • Place of Presentation: Bail, Indonesia
  • Year and Date: 2012-09-12