| Project/Area Number |
24792283
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
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| Research Collaborator |
YANAGITA Takeshi 岡山大学, 岡山大学病院, 助教 (90534793)
KAMIOKA Hiroshi 岡山大学, 大学院・医歯薬学総合研究科, 教授 (80253219)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | 小胞体ストレス / 歯の移動 / 実験的歯の移動 |
|---|
| Research Abstract |
The detailed mechanisms of orthodontic tooth movement have not been revealed. On the other hand, it was revealed that endoplasmic reticulum stress induced that cell survival and cell necrosis. The aim of this study was to examine the participation of the endoplasmic reticulum stress in periodontal membrane and the alveolar bone using an experimental tooth movement. Because the endoplasmic reticulum stress marker expressed in bone addition and the hypoxia situation, it was suggested that endoplasmic reticulum stress participated in the orthodontic tooth movement.
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