Mastication habits promote development of liver function through myokines
Project/Area Number |
24792348
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Social dentistry
|
Research Institution | Tohoku University |
Principal Investigator |
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 食習慣 / 糖代謝 / IL-6 |
Outline of Final Research Achievements |
Since obesity and diabetes are becoming increasingly prevalent in childhood, various problems associated with dietary habits-such as excessive eating of so-called soft food or fast food-are now matters of worldwide concern. However studies have revealed the mechanism that connects the eating habits and systemic metabolic disorder is not allowed yet. In this study, mice were fed with pellet- or powder-food from wearing until 6 months of age, the long-term eating of powdered food induced hyperglycemia and systemic-illness signs through myokines produced from masseter muscle. Among daily dietary habits, mastication of food of adequate hardness is an very important environmental factor in growth and development of an individual through the development of liver function.
|
Report
(4 results)
Research Products
(1 results)
-
[Journal Article] Long-term feeding on powdered food causes hyperglycemia and signs of systemic illness in mice.2014
Author(s)
Tsuchiya M, Niijima-Yaoita F, Yoneda H, Chiba K, Tsuchiya S, Hagiwara Y, Sasaki K, Sugawara S, Endo Y, Tan-No K, Watanabe M.
-
Journal Title
Life Sci.
Volume: 103
Issue: 1
Pages: 8-14
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant