| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Research Abstract |
Gustatory information processing could be modulated by olfaction. Not only gustation but also olfaction are processed in the insular cortex(IC). However, little information is available how these sensory inputs are integrated in the IC. The present study, aimed to examine the spatiotemporal dynamics of excitatory propagation in the IC induced by simultaneous stimulation of the parvicellular part of ventroposteromedial thalamic nucleus(VPMpc) and olfactory bulb(OB). We performed in vivo optical imaging with a voltage sensitive dye.
The excitatory regions by stimulating the either OB or VPMpc were segregated except for the agranular region(AI). The excitatory signals in the AI showed an additive effect of simultaneous stimulations to the OB and VPMpc. Our data raise the possibility that a part of integration of gustatory and odor sense were carried out in AI. These results suggest that the AI may play a role in integrating the gustatory and olfactory information.
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