Effects of appetite-regulating hormones on weight loss during structured exercise intervention.

• Project/Area Number: 24800005
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Applied health science
• Research Institution: Osaka University of Economics (2013-2014); University of Tsukuba (2012)
• Principal Investigator: ETO Miki 大阪経済大学, 人間科学部, 講師 (60633948)
• Project Period (FY): 2012-08-31 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥3,806,793 (Direct Cost: ¥2,928,303、Indirect Cost: ¥878,490); Fiscal Year 2014: ¥816,793 (Direct Cost: ¥628,303、Indirect Cost: ¥188,490); Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 身体活動 / 食欲調整ホルモン / 減量 / 肥満

Outline of Final Research Achievements

Overweight or obese Japanese who participated in exercise intervention trial were classified as responders or non-responders based on whether they meet an expected amount of weight loss. The aims of this study were (1) to compare blood levels of appetite-suppressing hormone between responders and non-responders at baseline, and (2) to compare the exercise-induced changes in appetite-suppressing between the two. The mean changes in body weight (-2.4 ± 3.2 kg) and moderate-vigorous physical activity (+183 ± 107 min/wk) were significant (P < 0.05). However, (1) appetite-suppressing hormone at baseline and (2) their changes during exercise intervention did not differ between responders and non-responders. These findings suggest that baseline levels and its response of appetite-suppressing hormones may not predict exercise-induced weight loss.