| Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
Among carbohydrates which are polymers of monosaccharaides, glycoconjugates bind to glycoproteins and play important and various roles in the process of development, differentiation, immunity, canceration, and infection. Owing to the recent development of mass spectrometry and liquid chromatography, information about glycoconjugates and lectins has rapidly accumulated. The accumulation is expected to activate researches about glycoinformatics. In our study, we obtained the following results: (1) Collection and curation of amino acid sequences for lectins, (2) Prediction of lectins from amino acid sequences using local Fisher discriminant analysis, and (3) Inference of amino acid subsequences that characterizes whether proteins are lectins or not.
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