Analysis of the toxicity of illegal harbals with approach of pharmacokinetics and toxicology
| Project/Area Number |
24890088
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Legal medicine
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| Research Institution | Mie University |
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Principal Investigator |
IKEMURA Mayumi 三重大学, 医学(系)研究科(研究院), 助教 (30515490)
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| Project Period (FY) |
2012-08-31 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 合法ハーブ / 薬物動態 / 乱用薬物 / ＪＷＨ－２０３ / ＭＰＨＰ / JWH-203 / MPHP / 分取薄層クロマトグラフ法 / JWH-251 |
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| Research Abstract |
In this study, we analyze the component of illegal harbals and investigate the correlation among the respiratory intake of illegal harbals, blood concentration and toxicity. We detected the regulated compound,"JWH-203", from the illegal harbals obtained in our laboratory, suggesting that the illegal harbals should contain the regulated compounds. It is suggested that the pharmacokinetics and toxicity of illegal harbals may differ depending on the variety, whereas the component of illegal harbals may not be detected in blood with lethal doses.
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Report
(3 results)
Research Products
(13 results)
