| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Research Abstract |
The results of NMR showed several peaks at 26, 62 and 170 ppm in the NMR spectrum shifted after UV irradiation. The shifts at 26, and 62 ppm suggested changes in fundermental structures including CH2. The changes at 26 and 62 ppm were clear under the condition with water. These results suggest that water may play an important role in accelerating molecular structural changes in collagen after UV irradiation and inter-molecular bond associated with water was produced at CH2chain after UV irradiation with water. The change at 170 ppm suggested that the C=O bond in proline converted into a hydrogen bondor an inter-molecular bond associated with water.
Structural changes in C=O and CH2 of type I collagen may be one of the reasons for strengthening human dentin after UV irradiation.
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