Analysis and identification of early diagnostic markers of metastasis in oral cancer
Project/Area Number |
24890175
|
Research Category |
Grant-in-Aid for Research Activity Start-up
|
Allocation Type | Single-year Grants |
Research Field |
Surgical dentistry
|
Research Institution | Kumamoto University |
Principal Investigator |
TANAKA TAKUYA 熊本大学, 医学部附属病院, 非常勤診療医師 (30631767)
|
Project Period (FY) |
2012-08-31 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 臨床腫瘍学 / 口腔癌 / 転移 / 転移マーカー / マイクロアレイ |
Research Abstract |
Oral Squamous Cell Carcinoma (OSCC) is in serious disease patient quality of life and life-threatening. In the treatment of oral Squamous Cell Carcinoma (OSCC), operative therapy and chemotherapy-radiation x-ray, and greatly contributed to improve the survival rate of patients with cancer and recurrences. But distant metastasis suppressor is difficult in the current development of a new treatment is desired. Applicant transplant, oral Squamous Cell Carcinoma (OSCC) cell line in nude mice and the successful establishment of the and create a model from a high metastatic spread to the lung. And micro-array analysis, discovery and identification as a candidate gene admitted Angptl4 (angiopoietin-like protein 4) upswing.
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Report
(3 results)
Research Products
(4 results)