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Analysis and identification of early diagnostic markers of metastasis in oral cancer

Research Project

Project/Area Number 24890175
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Surgical dentistry
Research InstitutionKumamoto University

Principal Investigator

TANAKA TAKUYA  熊本大学, 医学部附属病院, 非常勤診療医師 (30631767)

Project Period (FY) 2012-08-31 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords臨床腫瘍学 / 口腔癌 / 転移 / 転移マーカー / マイクロアレイ
Research Abstract

Oral Squamous Cell Carcinoma (OSCC) is in serious disease patient quality of life and life-threatening. In the treatment of oral Squamous Cell Carcinoma (OSCC), operative therapy and chemotherapy-radiation x-ray, and greatly contributed to improve the survival rate of patients with cancer and recurrences. But distant metastasis suppressor is difficult in the current development of a new treatment is desired. Applicant transplant, oral Squamous Cell Carcinoma (OSCC) cell line in nude mice and the successful establishment of the and create a model from a high metastatic spread to the lung. And micro-array analysis, discovery and identification as a candidate gene admitted Angptl4 (angiopoietin-like protein 4) upswing.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • Research Products

    (4 results)

All 2012

All Presentation (4 results)

  • [Presentation] 高転移性口腔扁平上皮癌におけるNF-kBの役割とその抑制効果に関する研究2012

    • Author(s)
      田中拓也
    • Organizer
      第50回日本癌治療学会総会神奈川
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] NBD peptideによるNF-kBの選択的抑制は高転移扁平上皮癌の転移を阻害する2012

    • Author(s)
      田中拓也
    • Organizer
      第57回日本口腔外科学会総会神奈川
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2013 Final Research Report
  • [Presentation] NBD peptideによるNF-κBの選択的抑制は高転移性扁平上皮癌の転移を阻害する2012

    • Author(s)
      田中 拓也
    • Organizer
      第58回(公社)日本口腔外科学会総会・学術大会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2012 Annual Research Report
  • [Presentation] 高転移性口腔扁平上皮癌におけるNF-κBの役割とその抑制効果に関する研究2012

    • Author(s)
      田中 拓也
    • Organizer
      第50回日本癌治療学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2012 Annual Research Report

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Published: 2012-11-27   Modified: 2019-07-29  

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