Research Project
Grant-in-Aid for Research Activity Start-up
The minimal capacity of mature cardiomyocte regeneration is one of the factors which determines the poor prognosis of heart failure. If we can proliferate cardiomyocytes and regenerate the heart, we will be able to completely cure heart failure. We planned to explore a novel cardiomyocyte cell cycle regulator by utilizing a fluorescent ubiquitination-based cell cycle indicator. We identified a protein which the expression level changes during the proliferation phase of cell cycle. We are analyzing the function of this candidate protein by over-expressing and deleting it in cardiomyocyte.
All 2014 2013 Other
All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (2 results)
J.Mol. Cell. Cardiol.
Volume: S0022-2828(14) Pages: 97-2
10.1016/j.yjmcc.2014.03.020
Journal of Molecular and Cellular Cardiology
Volume: 印刷中