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剛直さと柔軟さを内包する金属錯体の精密化で拓く複雑化合物の高度分子変換

Research Project

Project/Area Number 24K02159
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Basic Section 47050:Environmental and natural pharmaceutical resources-related
Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
Research InstitutionMicrobial Chemistry Research Foundation

Principal Investigator

野田 秀俊  公益財団法人微生物化学研究会, 微生物化学研究所, 主席研究員 (40771738)

Project Period (FY) 2024-04-01 – 2027-03-31
Project Status Granted (Fiscal Year 2024)
Budget Amount *help
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2026: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2025: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2024: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Keywords外輪型二核金属錯体 / 配座異性体 / 非結合性相互作用
Outline of Research at the Start

外輪型二核金属錯体の配座はその触媒機能と密接に関わっている。しかし配位子設計段階では錯体配座を事前に予見することが困難なため,これまで合理的な触媒設計が妨げられてきた。本研究では代表者が最近確立した所望の錯体配座を確実に取得できる配位子設計法を触媒反応場の合理的精密設計法へと昇華させ,複雑化合物の高度分子変換の実現を目指す。

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Published: 2024-04-11   Modified: 2024-06-24  

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