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In vivo polymer synthesis for therapeutic application via glycosylated artificial metalloenzymes

Research Project

Project/Area Number 24K08629
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 37030:Chemical biology-related
Research InstitutionInstitute of Physical and Chemical Research

Principal Investigator

張 宗哲  国立研究開発法人理化学研究所, 開拓研究本部, 研究員 (00774853)

Project Period (FY) 2024-04-01 – 2027-03-31
Project Status Granted (Fiscal Year 2024)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2026: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2025: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2024: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
KeywordsArtificial metalloenzyme / polymer / In vivo synthesis
Outline of Research at the Start

The aim of proposal is to develop an innovative therapeutic
method based on in vivo localized polymer synthesis via glycosylated artificial metalloenzymes. The
method not only avoids problems mentioned above, but also prevents unintended side effects against
untargeted cells.

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Published: 2024-04-05   Modified: 2024-06-24  

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